* Move virtualenv creation out of TestPipEnvironment
* Remove global state and force explicit use of TestPipEnvironment
  instances
* Remove "backup" virtualenv copying and instead create new
  virtual environments each time.
* Remove the monkeypatched "PyPICache" functionality
* Remove things that were not being used anymore and were dead
  weight
* Remove sitecustomize support which was primarily used to
  monkeypatch the "PyPICache" but was used in one or two other
  tests.