diff --git a/adjust.go b/adjust.go
index bae49bc94a117a0e9539f6d89a9d201f8a326314..9346bd1a6f9ab2e7ac9b996ef30242418a860740 100644
--- a/adjust.go
+++ b/adjust.go
@@ -471,12 +471,12 @@ func (af *arrayFormulaOperandToken) setCoordinates() error {
 		}
 		var c, r int
 		if col {
-			if cellRef.Row = TotalRows; i == 1 {
+			if cellRef.Row = TotalRows; i == 0 {
 				cellRef.Row = 1
 			}
 		}
 		if row {
-			if cellRef.Col = MaxColumns; i == 1 {
+			if cellRef.Col = MaxColumns; i == 0 {
 				cellRef.Col = 1
 			}
 		}
diff --git a/styles.go b/styles.go
index 489ce1de5cfe69d92e0566ac31ef089c0cae062e..54635042ac04c9dc6bc757a5c73eef861513ce2d 100644
--- a/styles.go
+++ b/styles.go
@@ -2760,13 +2760,9 @@ func (f *File) SetConditionalFormat(sheet, rangeRef string, opts []ConditionalFo
 	if err != nil {
 		return err
 	}
-	if strings.Contains(rangeRef, ":") {
-		rect, err := rangeRefToCoordinates(rangeRef)
-		if err != nil {
-			return err
-		}
-		_ = sortCoordinates(rect)
-		rangeRef, _ = f.coordinatesToRangeRef(rect, strings.Contains(rangeRef, "$"))
+	SQRef, mastCell, err := prepareConditionalFormatRange(rangeRef)
+	if err != nil {
+		return err
 	}
 	// Create a pseudo GUID for each unique rule.
 	var rules int
@@ -2796,7 +2792,7 @@ func (f *File) SetConditionalFormat(sheet, rangeRef string, opts []ConditionalFo
 				drawFunc, ok := drawContFmtFunc[vt]
 				if ok {
 					priority := rules + i
-					rule, x14rule := drawFunc(priority, ct, strings.Split(rangeRef, ":")[0],
+					rule, x14rule := drawFunc(priority, ct, mastCell,
 						fmt.Sprintf("{00000000-0000-0000-%04X-%012X}", f.getSheetID(sheet), priority), &opt)
 					if rule == nil {
 						return ErrParameterInvalid
@@ -2817,12 +2813,53 @@ func (f *File) SetConditionalFormat(sheet, rangeRef string, opts []ConditionalFo
 	}
 
 	ws.ConditionalFormatting = append(ws.ConditionalFormatting, &xlsxConditionalFormatting{
-		SQRef:  rangeRef,
+		SQRef:  SQRef,
 		CfRule: cfRule,
 	})
 	return err
 }
 
+// prepareConditionalFormatRange returns checked cell range and master cell
+// reference by giving conditional formatting range reference.
+func prepareConditionalFormatRange(rangeRef string) (string, string, error) {
+	var SQRef, mastCell string
+	if rangeRef == "" {
+		return SQRef, mastCell, ErrParameterRequired
+	}
+	rangeRef = strings.ReplaceAll(rangeRef, ",", " ")
+	for i, cellRange := range strings.Split(rangeRef, " ") {
+		var cellNames []string
+		for j, ref := range strings.Split(cellRange, ":") {
+			if j > 1 {
+				return SQRef, mastCell, ErrParameterInvalid
+			}
+			cellRef, col, row, err := parseRef(ref)
+			if err != nil {
+				return SQRef, mastCell, err
+			}
+			var c, r int
+			if col {
+				if cellRef.Row = TotalRows; j == 0 {
+					cellRef.Row = 1
+				}
+			}
+			if row {
+				if cellRef.Col = MaxColumns; j == 0 {
+					cellRef.Col = 1
+				}
+			}
+			c, r = cellRef.Col, cellRef.Row
+			cellName, _ := CoordinatesToCellName(c, r)
+			cellNames = append(cellNames, cellName)
+			if i == 0 && j == 0 {
+				mastCell = cellName
+			}
+		}
+		SQRef += strings.Join(cellNames, ":") + " "
+	}
+	return strings.TrimSuffix(SQRef, " "), mastCell, nil
+}
+
 // appendCfRule provides a function to append rules to conditional formatting.
 func (f *File) appendCfRule(ws *xlsxWorksheet, rule *xlsxX14CfRule) error {
 	var (
diff --git a/styles_test.go b/styles_test.go
index 9680fab70475be9dbb4e14f0c510f80da1df9fc5..9267da951e25228e66e8e14ec76da70749c8aacf 100644
--- a/styles_test.go
+++ b/styles_test.go
@@ -178,6 +178,10 @@ func TestSetConditionalFormat(t *testing.T) {
 		assert.NoError(t, f.SetConditionalFormat("Sheet1", ref, condFmts))
 	}
 	f = NewFile()
+	// Test creating a conditional format without cell reference
+	assert.Equal(t, ErrParameterRequired, f.SetConditionalFormat("Sheet1", "", nil))
+	// Test creating a conditional format with invalid cell reference
+	assert.Equal(t, ErrParameterInvalid, f.SetConditionalFormat("Sheet1", "A1:A2:A3", nil))
 	// Test creating a conditional format with existing extension lists
 	ws, ok := f.Sheet.Load("xl/worksheets/sheet1.xml")
 	assert.True(t, ok)
@@ -272,11 +276,11 @@ func TestGetConditionalFormats(t *testing.T) {
 		{{Type: "icon_set", IconStyle: "3Arrows", ReverseIcons: true, IconsOnly: true}},
 	} {
 		f := NewFile()
-		err := f.SetConditionalFormat("Sheet1", "A2:A1", format)
+		err := f.SetConditionalFormat("Sheet1", "A2:A1,B:B,2:2", format)
 		assert.NoError(t, err)
 		opts, err := f.GetConditionalFormats("Sheet1")
 		assert.NoError(t, err)
-		assert.Equal(t, format, opts["A1:A2"])
+		assert.Equal(t, format, opts["A2:A1 B1:B1048576 A2:XFD2"])
 	}
 	// Test get multiple conditional formats
 	f := NewFile()