diff --git a/activerecord/lib/active_record/connection_adapters/abstract_mysql_adapter.rb b/activerecord/lib/active_record/connection_adapters/abstract_mysql_adapter.rb
index f453e717ed1f10d00580074bf166ef4c47172ccf..22b71fbaba10ce86f857a58201d9f300f00799a8 100644
--- a/activerecord/lib/active_record/connection_adapters/abstract_mysql_adapter.rb
+++ b/activerecord/lib/active_record/connection_adapters/abstract_mysql_adapter.rb
@@ -607,10 +607,10 @@ def primary_keys(table_name) # :nodoc:
       end
 
       def case_sensitive_comparison(table, attribute, column, value)
-        if value.nil? || column.case_sensitive?
-          super
-        else
+        if !value.nil? && column.collation && !column.case_sensitive?
           table[attribute].eq(Arel::Nodes::Bin.new(Arel::Nodes::BindParam.new))
+        else
+          super
         end
       end
 
diff --git a/activerecord/test/cases/adapters/mysql2/case_sensitivity_test.rb b/activerecord/test/cases/adapters/mysql2/case_sensitivity_test.rb
index 963116f08ac080479b5f8cc9311da2bdcc6c83a0..9cb05119a20caed426bb99f522676f9bb1a29f25 100644
--- a/activerecord/test/cases/adapters/mysql2/case_sensitivity_test.rb
+++ b/activerecord/test/cases/adapters/mysql2/case_sensitivity_test.rb
@@ -51,4 +51,13 @@ def test_case_sensitive_comparison_for_cs_column
     cs_uniqueness_query = queries.detect { |q| q.match(/string_cs_column/) }
     assert_no_match(/binary/i, cs_uniqueness_query)
   end
+
+  def test_case_sensitive_comparison_for_binary_column
+    CollationTest.validates_uniqueness_of(:binary_column, case_sensitive: true)
+    CollationTest.create!(binary_column: 'A')
+    invalid = CollationTest.new(binary_column: 'A')
+    queries = assert_sql { invalid.save }
+    bin_uniqueness_query = queries.detect { |q| q.match(/binary_column/) }
+    assert_no_match(/\bBINARY\b/, bin_uniqueness_query)
+  end
 end
diff --git a/activerecord/test/schema/mysql2_specific_schema.rb b/activerecord/test/schema/mysql2_specific_schema.rb
index 101e6579824620a5afdb3fd0a704944b7bc8c32c..5a49b38457b26d064f11953936fa2a4b96607deb 100644
--- a/activerecord/test/schema/mysql2_specific_schema.rb
+++ b/activerecord/test/schema/mysql2_specific_schema.rb
@@ -33,6 +33,7 @@
   create_table :collation_tests, id: false, force: true do |t|
     t.string :string_cs_column, limit: 1, collation: 'utf8_bin'
     t.string :string_ci_column, limit: 1, collation: 'utf8_general_ci'
+    t.binary :binary_column,    limit: 1
   end
 
   ActiveRecord::Base.connection.execute <<-SQL