diff --git a/paddle/fluid/inference/api/analysis_config.cc b/paddle/fluid/inference/api/analysis_config.cc
index bf541b4d1b0a0aacb822a949b2478a1c306511d3..2beedaa2f4490610f602a39356dccddc232cb4dd 100644
--- a/paddle/fluid/inference/api/analysis_config.cc
+++ b/paddle/fluid/inference/api/analysis_config.cc
@@ -16,6 +16,7 @@
 #include <string>
 #include <tuple>
 
+#include "paddle/fluid/inference/api/helper.h"
 #include "paddle/fluid/inference/api/paddle_analysis_config.h"
 #include "paddle/fluid/inference/api/paddle_pass_builder.h"
 #include "paddle/fluid/inference/utils/table_printer.h"
@@ -40,6 +41,12 @@ extern const std::vector<std::string> kTRTSubgraphPasses;
 extern const std::vector<std::string> kDlnneSubgraphPasses;
 extern const std::vector<std::string> kLiteSubgraphPasses;
 
+AnalysisConfig::AnalysisConfig() {
+  // NOTE(liuyuanle): Why put the following code here?
+  // ref to https://github.com/PaddlePaddle/Paddle/pull/50864
+  inference::InitGflagsFromEnv();
+}
+
 PassStrategy *AnalysisConfig::pass_builder() const {
   if (!pass_builder_.get()) {
     if (use_gpu_) {
diff --git a/paddle/fluid/inference/api/analysis_predictor.cc b/paddle/fluid/inference/api/analysis_predictor.cc
index e8888940a99ac939cae45757ebe26c961b21949b..7b12567a33f97e303c3fa9ff685183b31790e07b 100644
--- a/paddle/fluid/inference/api/analysis_predictor.cc
+++ b/paddle/fluid/inference/api/analysis_predictor.cc
@@ -1497,32 +1497,6 @@ CreatePaddlePredictor<AnalysisConfig, PaddleEngineKind::kAnalysis>(
         if (std::getenv("FLAGS_initial_cpu_memory_in_mb") == nullptr) {
           SetGflag("initial_cpu_memory_in_mb", "0");
         }
-
-        // support set gflags from environment.
-        std::vector<std::string> gflags;
-        const phi::ExportedFlagInfoMap &env_map = phi::GetExportedFlagInfoMap();
-        std::ostringstream os;
-        for (auto &pair : env_map) {
-          os << pair.second.name << ",";
-        }
-        std::string tryfromenv_str = os.str();
-        if (!tryfromenv_str.empty()) {
-          tryfromenv_str.pop_back();
-          tryfromenv_str = "--tryfromenv=" + tryfromenv_str;
-          gflags.push_back(tryfromenv_str);
-        }
-        if (framework::InitGflags(gflags)) {
-          VLOG(3)
-              << "The following gpu analysis configurations only take effect "
-                 "for the first predictor: ";
-          for (const auto &gflag : gflags) {
-            VLOG(3) << gflag;
-          }
-        } else {
-          LOG(WARNING) << "The one-time configuration of analysis predictor "
-                          "failed, which may be due to native predictor called "
-                          "first and its configurations taken effect.";
-        }
       });
 
       if (config.thread_local_stream_enabled() &&
diff --git a/paddle/fluid/inference/api/helper.cc b/paddle/fluid/inference/api/helper.cc
index 3454c5c8fd17b5221c4ace93d56a88fc574526d1..3fd8ed490fe458b40ad00f739c802ee87a688828 100644
--- a/paddle/fluid/inference/api/helper.cc
+++ b/paddle/fluid/inference/api/helper.cc
@@ -16,6 +16,7 @@
 
 #include "paddle/fluid/framework/custom_operator.h"
 #include "paddle/fluid/framework/operator.h"
+#include "paddle/fluid/platform/init.h"
 #include "paddle/phi/api/ext/op_meta_info.h"
 
 namespace paddle {
@@ -59,5 +60,22 @@ void RegisterAllCustomOperator() {
   }
 }
 
+void InitGflagsFromEnv() {
+  // support set gflags from environment.
+  std::vector<std::string> gflags;
+  const phi::ExportedFlagInfoMap &env_map = phi::GetExportedFlagInfoMap();
+  std::ostringstream os;
+  for (auto &pair : env_map) {
+    os << pair.second.name << ",";
+  }
+  std::string tryfromenv_str = os.str();
+  if (!tryfromenv_str.empty()) {
+    tryfromenv_str.pop_back();
+    tryfromenv_str = "--tryfromenv=" + tryfromenv_str;
+    gflags.push_back(tryfromenv_str);
+  }
+  framework::InitGflags(gflags);
+}
+
 }  // namespace inference
 }  // namespace paddle
diff --git a/paddle/fluid/inference/api/helper.h b/paddle/fluid/inference/api/helper.h
index de92281bb07a747860652e2167c176036871244f..92b6f12338f79742a42df3c04290a5c443243c70 100644
--- a/paddle/fluid/inference/api/helper.h
+++ b/paddle/fluid/inference/api/helper.h
@@ -432,6 +432,8 @@ static bool IsFileExists(const std::string &path) {
 
 void RegisterAllCustomOperator();
 
+void InitGflagsFromEnv();
+
 static inline double ToMegaBytes(size_t bytes) {
   return static_cast<double>(bytes) / (1 << 20);
 }
diff --git a/paddle/fluid/inference/api/paddle_analysis_config.h b/paddle/fluid/inference/api/paddle_analysis_config.h
index 8e12f15e7a01819c7364238c85760d897a800eb3..c1a18694fe1206ad8020dd0dfdb686a20940784d 100644
--- a/paddle/fluid/inference/api/paddle_analysis_config.h
+++ b/paddle/fluid/inference/api/paddle_analysis_config.h
@@ -138,7 +138,7 @@ struct DistConfig {
 /// and loading it into AnalysisPredictor.
 ///
 struct PD_INFER_DECL AnalysisConfig {
-  AnalysisConfig() = default;
+  AnalysisConfig();
   ///
   /// \brief Construct a new AnalysisConfig from another
   /// AnalysisConfig.
diff --git a/paddle/fluid/platform/init.cc b/paddle/fluid/platform/init.cc
index b53a65e7e61f3aadce703c6158388ce7c0101e6c..8410ea0b2192a7d3e97b65087ec46a1082d2a755 100644
--- a/paddle/fluid/platform/init.cc
+++ b/paddle/fluid/platform/init.cc
@@ -85,7 +85,6 @@ namespace framework {
 
 std::once_flag gflags_init_flag;
 std::once_flag glog_init_flag;
-std::once_flag npu_init_flag;
 std::once_flag memory_method_init_flag;
 
 bool InitGflags(std::vector<std::string> args) {