diff --git a/paddle/fluid/framework/ir/mkldnn/mkldnn_placement_pass.cc b/paddle/fluid/framework/ir/mkldnn/mkldnn_placement_pass.cc
index 8d8d7feacfb9148a9dd1debf9f6e96b3a4578f47..c966c46e06b16e8e48bd194ba2ffc05d420e2e9a 100644
--- a/paddle/fluid/framework/ir/mkldnn/mkldnn_placement_pass.cc
+++ b/paddle/fluid/framework/ir/mkldnn/mkldnn_placement_pass.cc
@@ -69,8 +69,24 @@ inline bool FoundPhiOneDNNKernelWithCorrectDataType(
 
 bool MKLDNNPlacementPass::IsSupport(const Node* op) const {
   if (FoundOneDNNKernelWithCorrectDataType(op) ||
-      FoundPhiOneDNNKernelWithCorrectDataType(op))
-    return true;
+      FoundPhiOneDNNKernelWithCorrectDataType(op)) {
+    // For interpolate ops, there's a little difference between Paddle and
+    // DNNL.
+    // If run DNNL interpolate ops, manual set AnalysisConfig and apply
+    // the corresponding pass.
+    const std::vector<std::string> not_default_op_types = {"bilinear_interp",
+                                                           "nearest_interp",
+                                                           "trilinear_interp",
+                                                           "bicubic_interp",
+                                                           "linear_interp",
+                                                           "bilinear_interp_v2",
+                                                           "linear_interp_v2"};
+    bool is_interpolate_op =
+        std::find(not_default_op_types.begin(),
+                  not_default_op_types.end(),
+                  op->Op()->Type()) != not_default_op_types.end();
+    return !is_interpolate_op;
+  }
   return false;
 }
 
diff --git a/paddle/fluid/inference/api/paddle_pass_builder.cc b/paddle/fluid/inference/api/paddle_pass_builder.cc
index 43d452820e0f42ea9c594099bc4f859ed27f066f..8b1399515eda090e54c982761ed8c1a719c196ff 100644
--- a/paddle/fluid/inference/api/paddle_pass_builder.cc
+++ b/paddle/fluid/inference/api/paddle_pass_builder.cc
@@ -363,7 +363,6 @@ void CpuPassStrategy::EnableMKLDNN() {
              "conv_transpose_eltwiseadd_bn_fuse_pass",  //
              "conv_bias_mkldnn_fuse_pass",              //
              "conv_transpose_bias_mkldnn_fuse_pass",
-             "interpolate_mkldnn_pass",
              // TODO(baoachun): Need to support 5-dimensional input.
              // "conv3d_bias_mkldnn_fuse_pass",  //
              "conv_elementwise_add_mkldnn_fuse_pass",