diff --git a/drivers/pci/msi.c b/drivers/pci/msi.c
index 496ed9130600e90c2a78bf1dd815615db7594059..e066071678580271e68da7d962fa3fccfb69ab45 100644
--- a/drivers/pci/msi.c
+++ b/drivers/pci/msi.c
@@ -1441,6 +1441,8 @@ struct irq_domain *pci_msi_create_irq_domain(struct fwnode_handle *fwnode,
 		pci_msi_domain_update_chip_ops(info);
 
 	info->flags |= MSI_FLAG_ACTIVATE_EARLY;
+	if (IS_ENABLED(CONFIG_GENERIC_IRQ_RESERVATION_MODE))
+		info->flags |= MSI_FLAG_MUST_REACTIVATE;
 
 	domain = msi_create_irq_domain(fwnode, info, parent);
 	if (!domain)