diff --git a/target/s390x/insn-data.def b/target/s390x/insn-data.def
index add174b7938153a4a4e01a40c95843ef38a6f034..07868ff082ae1b5252f039db10e2045453e99721 100644
--- a/target/s390x/insn-data.def
+++ b/target/s390x/insn-data.def
@@ -1094,6 +1094,8 @@
     F(0xe7b4, VGFM,    VRR_c, V,   0, 0, 0, 0, vgfm, 0, IF_VEC)
 /* VECTOR GALOIS FIELD MULTIPLY SUM AND ACCUMULATE */
     F(0xe7bc, VGFMA,   VRR_d, V,   0, 0, 0, 0, vgfma, 0, IF_VEC)
+/* VECTOR LOAD COMPLEMENT */
+    F(0xe7de, VLC,     VRR_a, V,   0, 0, 0, 0, vlc, 0, IF_VEC)
 
 #ifndef CONFIG_USER_ONLY
 /* COMPARE AND SWAP AND PURGE */
diff --git a/target/s390x/translate_vx.inc.c b/target/s390x/translate_vx.inc.c
index 1db5d6d152c6649e3caae7897b7e6cadc1bd2c80..2fc06c7cf3ef952ccba24e559fe53d237a057a59 100644
--- a/target/s390x/translate_vx.inc.c
+++ b/target/s390x/translate_vx.inc.c
@@ -209,6 +209,9 @@ static void get_vec_element_ptr_i64(TCGv_ptr ptr, uint8_t reg, TCGv_i64 enr,
                      16)
 #define gen_gvec_dup64i(v1, c) \
     tcg_gen_gvec_dup64i(vec_full_reg_offset(v1), 16, 16, c)
+#define gen_gvec_fn_2(fn, es, v1, v2) \
+    tcg_gen_gvec_##fn(es, vec_full_reg_offset(v1), vec_full_reg_offset(v2), \
+                      16, 16)
 #define gen_gvec_fn_3(fn, es, v1, v2, v3) \
     tcg_gen_gvec_##fn(es, vec_full_reg_offset(v1), vec_full_reg_offset(v2), \
                       vec_full_reg_offset(v3), 16, 16)
@@ -1521,3 +1524,16 @@ static DisasJumpType op_vgfma(DisasContext *s, DisasOps *o)
                get_field(s->fields, v3), get_field(s->fields, v4), &g[es]);
     return DISAS_NEXT;
 }
+
+static DisasJumpType op_vlc(DisasContext *s, DisasOps *o)
+{
+    const uint8_t es = get_field(s->fields, m3);
+
+    if (es > ES_64) {
+        gen_program_exception(s, PGM_SPECIFICATION);
+        return DISAS_NORETURN;
+    }
+
+    gen_gvec_fn_2(neg, es, get_field(s->fields, v1), get_field(s->fields, v2));
+    return DISAS_NEXT;
+}