diff --git a/tests/qemuargv2xmldata/qemuargv2xml-hostdev-pci-address.xml b/tests/qemuargv2xmldata/qemuargv2xml-hostdev-pci-address.xml
index 77b484d32ee05aea9354ad8d9cc9825749a63df9..937238afa3410a909c7f0180508149d8336178a4 100644
--- a/tests/qemuargv2xmldata/qemuargv2xml-hostdev-pci-address.xml
+++ b/tests/qemuargv2xmldata/qemuargv2xml-hostdev-pci-address.xml
@@ -1,6 +1,6 @@
 <domain type='qemu'>
   <name>QEMUGuest2</name>
-  <uuid>c7a5fdbd-edaf-9466-926a-d65c16db1809</uuid>
+  <uuid>c7a5fdbd-edaf-9455-926a-d65c16db1809</uuid>
   <memory unit='KiB'>219100</memory>
   <currentMemory unit='KiB'>219100</currentMemory>
   <vcpu placement='static'>1</vcpu>
diff --git a/tests/qemuargv2xmldata/qemuargv2xml-misc-disable-s3.xml b/tests/qemuargv2xmldata/qemuargv2xml-misc-disable-s3.xml
index 3619c24e8fb6e5be9d4da4bfb170a4cee1ea3442..1545064e38bd1dae6f1412a6c7027c6620a76694 100644
--- a/tests/qemuargv2xmldata/qemuargv2xml-misc-disable-s3.xml
+++ b/tests/qemuargv2xmldata/qemuargv2xml-misc-disable-s3.xml
@@ -1,6 +1,6 @@
 <domain type='qemu'>
   <name>QEMUGuest1</name>
-  <uuid>8caaa98c-e7bf-5845-126a-1fc316bd1089</uuid>
+  <uuid>c7a5fdbd-edaf-9455-926a-d65c16db1809</uuid>
   <memory unit='KiB'>219100</memory>
   <currentMemory unit='KiB'>219100</currentMemory>
   <vcpu placement='static'>1</vcpu>
diff --git a/tests/qemuargv2xmldata/qemuargv2xml-misc-disable-suspends.xml b/tests/qemuargv2xmldata/qemuargv2xml-misc-disable-suspends.xml
index 30276e0d582dbf1d055d21adf2e5b6a8f80f6bf3..f6ebba9ffac631ae4093bc68510e42ce4294a8be 100644
--- a/tests/qemuargv2xmldata/qemuargv2xml-misc-disable-suspends.xml
+++ b/tests/qemuargv2xmldata/qemuargv2xml-misc-disable-suspends.xml
@@ -1,6 +1,6 @@
 <domain type='qemu'>
   <name>QEMUGuest1</name>
-  <uuid>8caaa98c-e7bf-5845-126a-1fc316bd1089</uuid>
+  <uuid>c7a5fdbd-edaf-9455-926a-d65c16db1809</uuid>
   <memory unit='KiB'>219100</memory>
   <currentMemory unit='KiB'>219100</currentMemory>
   <vcpu placement='static'>1</vcpu>
diff --git a/tests/qemuargv2xmldata/qemuargv2xml-misc-enable-s4.xml b/tests/qemuargv2xmldata/qemuargv2xml-misc-enable-s4.xml
index ac8b3f094c2425217b0d7e97e180820d55298b84..089622cc74a2a6898cb7295cdb9fdae9c9bc70b4 100644
--- a/tests/qemuargv2xmldata/qemuargv2xml-misc-enable-s4.xml
+++ b/tests/qemuargv2xmldata/qemuargv2xml-misc-enable-s4.xml
@@ -1,6 +1,6 @@
 <domain type='qemu'>
   <name>QEMUGuest1</name>
-  <uuid>8caaa98c-e7bf-5845-126a-1fc316bd1089</uuid>
+  <uuid>c7a5fdbd-edaf-9455-926a-d65c16db1809</uuid>
   <memory unit='KiB'>219100</memory>
   <currentMemory unit='KiB'>219100</currentMemory>
   <vcpu placement='static'>1</vcpu>
diff --git a/tests/qemuargv2xmldata/qemuargv2xml-pseries-disk.xml b/tests/qemuargv2xmldata/qemuargv2xml-pseries-disk.xml
index 39f4a1f7265719974738fea92b4ff22f40e0af02..44c3b1d535d46aa49c1f433ef26ceceabc515eb6 100644
--- a/tests/qemuargv2xmldata/qemuargv2xml-pseries-disk.xml
+++ b/tests/qemuargv2xmldata/qemuargv2xml-pseries-disk.xml
@@ -1,6 +1,6 @@
 <domain type='qemu'>
   <name>QEMUGuest1</name>
-  <uuid>87eedafe-eedc-4336-8130-ed9fe5dc90c8</uuid>
+  <uuid>c7a5fdbd-edaf-9455-926a-d65c16db1809</uuid>
   <memory unit='KiB'>524288</memory>
   <currentMemory unit='KiB'>524288</currentMemory>
   <vcpu placement='static'>1</vcpu>
diff --git a/tests/qemuargv2xmldata/qemuargv2xml-pseries-nvram.xml b/tests/qemuargv2xmldata/qemuargv2xml-pseries-nvram.xml
index 2da28323d8fade45308f2a0ed014d4507efd31cd..eafe49d94e4fa27f6260f3b52c03851f821831aa 100644
--- a/tests/qemuargv2xmldata/qemuargv2xml-pseries-nvram.xml
+++ b/tests/qemuargv2xmldata/qemuargv2xml-pseries-nvram.xml
@@ -1,6 +1,6 @@
 <domain type='qemu'>
   <name>QEMUGuest1</name>
-  <uuid>1ccfd97d-5eb4-478a-bbe6-88d254c16db7</uuid>
+  <uuid>c7a5fdbd-edaf-9455-926a-d65c16db1809</uuid>
   <memory unit='KiB'>524288</memory>
   <currentMemory unit='KiB'>524288</currentMemory>
   <vcpu placement='static'>1</vcpu>
diff --git a/tests/qemuargv2xmltest.c b/tests/qemuargv2xmltest.c
index f07818a4f23931f1df08bcaad3718227417eafe5..6650cf0344d5cd6d4be6244674b5f9e8f46ba650 100644
--- a/tests/qemuargv2xmltest.c
+++ b/tests/qemuargv2xmltest.c
@@ -23,8 +23,7 @@ static virQEMUDriver driver;
 
 static int blankProblemElements(char *data)
 {
-    if (virtTestClearLineRegex("<uuid>([[:alnum:]]|-)+</uuid>", data) < 0 ||
-        virtTestClearLineRegex("<memory.*>[[:digit:]]+</memory>", data) < 0 ||
+    if (virtTestClearLineRegex("<memory.*>[[:digit:]]+</memory>", data) < 0 ||
         virtTestClearLineRegex("<secret.*>", data) < 0 ||
         virtTestClearLineRegex("<currentMemory.*>[[:digit:]]+</currentMemory>",
                                data) < 0)
@@ -32,6 +31,19 @@ static int blankProblemElements(char *data)
     return 0;
 }
 
+static int testSanitizeDef(virDomainDefPtr vmdef)
+{
+    int ret = -1;
+
+    /* Remove UUID randomness */
+    if (virUUIDParse("c7a5fdbd-edaf-9455-926a-d65c16db1809", vmdef->uuid) < 0)
+        goto fail;
+
+    ret = 0;
+ fail:
+    return ret;
+}
+
 typedef enum {
     FLAG_EXPECT_WARNING     = 1 << 0,
 } virQemuXML2ArgvTestFlags;
@@ -79,6 +91,9 @@ static int testCompareXMLToArgvFiles(const char *xml,
         }
     }
 
+    if (testSanitizeDef(vmdef) < 0)
+        goto fail;
+
     if (!virDomainDefCheckABIStability(vmdef, vmdef)) {
         VIR_TEST_DEBUG("ABI stability check failed on %s", xml);
         goto fail;