diff --git a/arch/s390/lib/Makefile b/arch/s390/lib/Makefile
index 57ab40188d4bddab071505f1d5a204a82dca3ce5..5418d10dc2a819b030d01c985a5e8129d5b1e3ce 100644
--- a/arch/s390/lib/Makefile
+++ b/arch/s390/lib/Makefile
@@ -9,5 +9,9 @@ lib-$(CONFIG_SMP) += spinlock.o
 lib-$(CONFIG_KPROBES) += probes.o
 lib-$(CONFIG_UPROBES) += probes.o
 
+# Instrumenting memory accesses to __user data (in different address space)
+# produce false positives
+KASAN_SANITIZE_uaccess.o := n
+
 chkbss := mem.o
 include $(srctree)/arch/s390/scripts/Makefile.chkbss