diff --git a/src/libraries/Common/src/Interop/Unix/System.Native/Interop.ProcessorArchitecture.cs b/src/libraries/Common/src/Interop/Unix/System.Native/Interop.ProcessorArchitecture.cs
index 81dc2f936895eb9776dc9c7ed4f81f5b31cc044e..8b1ad552e7ddd6d7627bbf4e0bf0aec735f93380 100644
--- a/src/libraries/Common/src/Interop/Unix/System.Native/Interop.ProcessorArchitecture.cs
+++ b/src/libraries/Common/src/Interop/Unix/System.Native/Interop.ProcessorArchitecture.cs
@@ -14,7 +14,8 @@ internal enum ProcessorArchitecture
             x64,
             ARM,
             ARM64,
-            WASM
+            WASM,
+            S390x
         }
     }
 }
diff --git a/src/libraries/Native/Unix/System.Native/pal_runtimeinformation.c b/src/libraries/Native/Unix/System.Native/pal_runtimeinformation.c
index 56ad9f2a4240b22c3a21b4a02248192c12dac43e..504cb32e0d192116f3dae4ef88dd73737d8f0e8c 100644
--- a/src/libraries/Native/Unix/System.Native/pal_runtimeinformation.c
+++ b/src/libraries/Native/Unix/System.Native/pal_runtimeinformation.c
@@ -55,6 +55,8 @@ int32_t SystemNative_GetOSArchitecture()
     return ARCH_X86;
 #elif defined(TARGET_WASM)
     return ARCH_WASM;
+#elif defined(TARGET_S390X)
+    return ARCH_S390X;
 #else
 #error Unidentified Architecture
 #endif
@@ -78,6 +80,8 @@ int32_t SystemNative_GetProcessArchitecture()
     return ARCH_X86;
 #elif defined(TARGET_WASM)
     return ARCH_WASM;
+#elif defined(TARGET_S390X)
+    return ARCH_S390X;
 #else
 #error Unidentified Architecture
 #endif
diff --git a/src/libraries/Native/Unix/System.Native/pal_runtimeinformation.h b/src/libraries/Native/Unix/System.Native/pal_runtimeinformation.h
index 8f233ae1e603b136c8554cf1555e480184d41fb3..ff7e91d7dad1da860ee4966e35b551e25eb826a8 100644
--- a/src/libraries/Native/Unix/System.Native/pal_runtimeinformation.h
+++ b/src/libraries/Native/Unix/System.Native/pal_runtimeinformation.h
@@ -22,5 +22,6 @@ enum
     ARCH_X64,
     ARCH_ARM,
     ARCH_ARM64,
-    ARCH_WASM
+    ARCH_WASM,
+    ARCH_S390X
 };
diff --git a/src/libraries/System.Runtime.InteropServices.RuntimeInformation/ref/System.Runtime.InteropServices.RuntimeInformation.cs b/src/libraries/System.Runtime.InteropServices.RuntimeInformation/ref/System.Runtime.InteropServices.RuntimeInformation.cs
index f5ed97de3b96b94e2ae35cec2fe860a83727cd60..576f7b08f9493e3dac8b012df82283d1a02cc676 100644
--- a/src/libraries/System.Runtime.InteropServices.RuntimeInformation/ref/System.Runtime.InteropServices.RuntimeInformation.cs
+++ b/src/libraries/System.Runtime.InteropServices.RuntimeInformation/ref/System.Runtime.InteropServices.RuntimeInformation.cs
@@ -13,6 +13,7 @@ public enum Architecture
         Arm = 2,
         Arm64 = 3,
         Wasm = 4,
+        S390x = 5,
     }
     public readonly partial struct OSPlatform : System.IEquatable<System.Runtime.InteropServices.OSPlatform>
     {
diff --git a/src/libraries/System.Runtime.InteropServices.RuntimeInformation/src/System/Runtime/InteropServices/RuntimeInformation/Architecture.cs b/src/libraries/System.Runtime.InteropServices.RuntimeInformation/src/System/Runtime/InteropServices/RuntimeInformation/Architecture.cs
index fd77f67601c9b51000fd1e0ba5a0d5dfe58a0d28..2c52a9b8ea433cd9274beebcd105c621eb6aa8c1 100644
--- a/src/libraries/System.Runtime.InteropServices.RuntimeInformation/src/System/Runtime/InteropServices/RuntimeInformation/Architecture.cs
+++ b/src/libraries/System.Runtime.InteropServices.RuntimeInformation/src/System/Runtime/InteropServices/RuntimeInformation/Architecture.cs
@@ -9,6 +9,7 @@ public enum Architecture
         X64,
         Arm,
         Arm64,
-        Wasm
+        Wasm,
+        S390x
     }
 }
diff --git a/src/libraries/System.Runtime.InteropServices.RuntimeInformation/src/System/Runtime/InteropServices/RuntimeInformation/RuntimeInformation.Unix.cs b/src/libraries/System.Runtime.InteropServices.RuntimeInformation/src/System/Runtime/InteropServices/RuntimeInformation/RuntimeInformation.Unix.cs
index 0a8147db34af52177187fbcf41bf6cba5d37f8e9..46b1a85d763c26fed6ae5ad79e006157a0239986 100644
--- a/src/libraries/System.Runtime.InteropServices.RuntimeInformation/src/System/Runtime/InteropServices/RuntimeInformation/RuntimeInformation.Unix.cs
+++ b/src/libraries/System.Runtime.InteropServices.RuntimeInformation/src/System/Runtime/InteropServices/RuntimeInformation/RuntimeInformation.Unix.cs
@@ -27,6 +27,8 @@ private static Architecture Map(Interop.Sys.ProcessorArchitecture arch)
                     return Architecture.Arm64;
                 case Interop.Sys.ProcessorArchitecture.WASM:
                     return Architecture.Wasm;
+                case Interop.Sys.ProcessorArchitecture.S390x:
+                    return Architecture.S390x;
                 case Interop.Sys.ProcessorArchitecture.x86:
                 default:
                     Debug.Assert(arch == Interop.Sys.ProcessorArchitecture.x86, "Unidentified Architecture");
diff --git a/src/libraries/System.Runtime.InteropServices.RuntimeInformation/tests/CheckArchitectureTests.cs b/src/libraries/System.Runtime.InteropServices.RuntimeInformation/tests/CheckArchitectureTests.cs
index a54b80285783b40c92f74520fe4cfd565712abcb..50c52fa853158f68155063bdac90f830184480d1 100644
--- a/src/libraries/System.Runtime.InteropServices.RuntimeInformation/tests/CheckArchitectureTests.cs
+++ b/src/libraries/System.Runtime.InteropServices.RuntimeInformation/tests/CheckArchitectureTests.cs
@@ -36,6 +36,10 @@ public void VerifyArchitecture()
                     Assert.Equal(Architecture.Wasm, processArch);
                     break;
 
+                case Architecture.S390x:
+                    Assert.Equal(Architecture.S390x, processArch);
+                    break;
+
                 default:
                     Assert.False(true, "Unexpected Architecture.");
                     break;