diff --git a/paddle/fluid/operators/CMakeLists.txt b/paddle/fluid/operators/CMakeLists.txt
index 7d6781c2c38822eaabb64eda9c76ff657bbdeeb8..3ae4e0ea01c4af761d1df074735692ed5b51ac06 100644
--- a/paddle/fluid/operators/CMakeLists.txt
+++ b/paddle/fluid/operators/CMakeLists.txt
@@ -163,7 +163,12 @@ function(op_library TARGET)
 
     # pybind USE_OP
     if (${pybind_flag} EQUAL 0)
+      # NOTE(*): activation use macro to regist the kernels, set use_op manually.
+      if(${TARGET} STREQUAL "activation")
+        file(APPEND ${pybind_file} "USE_OP(relu);\n")
+      else()
         file(APPEND ${pybind_file} "USE_OP(${TARGET});\n")
+      endif()
     endif()
 endfunction()